Atomic Force Microscopy for Biologists

by V. J. Morris, A. R. Kirby, A. P. Gunning

Publisher: Imperial College Press
ISBN: 184816467X

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Book Description

Atomic force microscopy (AFM) is part of a range of emerging microscopic methods for biologists which offer the magnification range of both the light and electron microscope, but allow imaging under the 'natural' conditions usually associated with the light microscope.

To biologists, AFM offers the prospect of high resolution images of biological material, images of molecules and their interactions even under physiological conditions, and the study of molecular processes in living systems. This book provides a realistic appreciation of the advantages and limitations of the technique and the present and future potential for improving the understanding of biological systems. The second edition of this bestseller has been updated to describe the latest developments in this exciting field, including a brand new chapter on force spectroscopy. The dramatic developments of AFM over the past ten years from a simple imaging tool to the multi-faceted, nano-manipulating technique that it is today are conveyed in a lively and informative narrative, which provides essential reading for students and experienced researchers alike.

Customer Reviews

"Atomic Force Microscopy for Biologists" is an excellent introduction for anybody wishing to enter this field. Nearly all aspects are covered. The book opens with an overview of the theory behind Atomic Force Microscopy and the different modes of use. This is presented in a concise manner without over-reliance on complex mathematical equations. Unlike many other volumes, practical advice on sample preparation techniques is provided for common systems such as proteins, cells and DNA. A comprehenive review of leading research in this area at the time of publication is sectioned by biomaterial type. Different approaches to imaging are tackled. The text is supported by numerous supporting images.

In summary I would strongly recommend this book to any biologist planning on carrying out research using SPM imaging technqiues and existing users in the field who wish to broaden their knowledge of SPM imaging and the research already carried out n common biological systems.